Symbol
Name
ID

Plxnb2
plexin B2
MGI:2154239

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Mouse Phenotypes

nervous system phenotype

abnormal radial glial cell morphology

abnormal cerebellar granule cell migration

abnormal neuronal precursor cell migration

decreased neuronal precursor proliferation

abnormal neural tube morphology

incomplete caudal neuropore closure

incomplete rostral neuropore closure

open neural tube

spina bifida

abnormal brain morphology

abnormal cerebellar foliation

abnormal cerebellar lobule formation

absent cerebellar foliation

abnormal cerebellum external granule cell layer morphology

abnormal olfactory bulb development

abnormal rostral migratory stream morphology

abnormal brain ventricle morphology

enlarged brain ventricles

abnormal choroid plexus morphology

abnormal striatum morphology

abnormal diencephalon morphology

abnormal olfactory bulb interneuron morphology

abnormal olfactory bulb granule cell morphology

abnormal olfactory bulb periglomerular cell morphology

abnormal olfactory bulb layer morphology

abnormal olfactory bulb internal plexiform layer morphology

abnormal olfactory bulb mitral cell layer morphology

abnormal cerebellum morphology

abnormal cerebellar cortex morphology

abnormal cerebellar Purkinje cell layer

ectopic Purkinje cell

abnormal cerebellar granule layer morphology

abnormal cerebellar granule cell morphology

ectopic cerebellar granule cells

small cerebellum

exencephaly

Availability

Mouse Genotype

Plxnb2^m597804Hubr/Plxnb2^m597804Hubr

Plxnb2^tm1Matl/Plxnb2^tm1Matl

Plxnb2^tm1Rkun/Plxnb2^tm1Rkun

Plxnb2^{tm1c(EUCOMM)Wtsi}/Plxnb2^tm1Matl
Tg(Nes-cre)1Kln/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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